Date:
Oct 08 2026 - Oct 10 2026
Time:
All day
Location:
Cambridge, Massachusetts
Category:
International Symposiums
On May 8-10, 2026, the 6th International Symposium on IgG4-Related Disease will bring together international experts to inform, debate, and discuss novel aspects in the field and to update the guidelines for diagnosing and treating IgG4-Related Disease.
RegisterThe IgG4ward! Foundation invites you to the 6th International Symposium on IgG4-RD
The 6th International Symposium on IgG4-related disease (IgG4-RD) will update the clinical guidelines on the diagnosis, treatment, and management of IgG4-RD since the 1st International Symposium in 2011. Other agenda topics include organ-specific manifestations, new thinking about pathology, the Granzyme K story, present and future treatment approaches, lessons from the MITIGATE and INDIGO clinical trials, and more.
The quick history of symposiums:
1st International Symposium, Boston (US) in 2011
Officially named the condition — “IgG4-related disease, and established other nomenclature and the pathology features of the disease.
2nd and 3rd International Symposia, Hawaii 2014 & 2017
Launched the first set of classification criteria for this condition, explored common clinical presentations of the disease, and established diagnostic standards for each organ involvement.
4th International Symposium, virtual mtg, Kitakyushu (Japan) 2021
Began to review treatment guidelines and ongoing investigational approaches to treatment.
5th International Symposium, Milan 2024
Informed, debated, and discussed disease classification, organ-specific manifestations, diagnostic features, immunopathogenesis, and present and future treatment approaches. Also, defined the IgG4-related disease activity score (IgG4-RDAS), a novel clinimetric tool to guide treatment decisions.
Expert-led sessions
Opportunities to connect with others clinicians and scientists
A supportive environment focused on learning, empowerment, and community
The Charles Hotel, Harvard Sqaure
Website: www.charleshotel.com
Address: One Bennett St Harvard Sq, Cambridge, Massachusetts, United States, 02138
Phone: +1 617-864-1200
Booking: Reservation link (preferential rates)
Agenda
Day 1 - October 8
8:00 - 12:00
MORNING SESSION
8:00
Welcome
8:20
Overview of the IgG4ward! Foundation international guidelines on the diagnosis, treatment, and management
8:40
Diagnosis guidelines highlights
9:40
Break
10:00
New thinking about the pathology of IgG4-RD
10:45
Orbital disease: Issues in diagnosis and treatment
11:30
Retroperitoneal fibrosis: What are our biggest challenges and how do we circumvent them?
12:00
Lunch
1:00 - 7:00
AFTERNOON SESSION
1:15
The pathophysiology of IgG4-RD
2:00
A knock-in mouse model of IgG4-RD
2:30
Long-term outcomes in type 1 autoimmune pancreatitis
3:00
Managing exocrine pancreatic insufficiency
3:30
Break
3:50
What is the long-term prognosis of IgG4-RD?
4:20
Oral presentations of the top abstracts
5:00–07:00
Poster viewing session
7:00
Conclude for the day
07:00
Speakers’ dinner and industry dinners
Day 2 - October 9
08:00 - 12:20
MORNING SESSION
8:00
Treatment guidelines highlights
9:00
The granzyme K story: Is this T cell the disease linchpin?
9:30
Which B lymphocytes are the key players in IgG4-RD?
10:00
Break
10:20
Emerging insights into the genetics of IgG4-RD
11:00
Tph cells versus T-follicular helper cells in IgG4-RD
11:40
Autoantibodies and autoantigens in IgG4-RD
12:20 - 1:45
Symposium photo in Harvard Yard, followed by lunch on your own in Harvard Square
1:45 - 04:30
AFTERNOON SESSION
1:45
Biggest lessons and recent data from MITIGATE
2:15
Biggest lessons and recent data from INDIGO
2:45
Break
3:00
Progress in current trials (RILIEF, ACE1831, other)
3:30
Next-generation immune reset in autoimmune disease: Cell-based and bi-specific strategies targeting B cells and possible application in IgG4-RD
4:30
Conclude for the day
6:00 - 9:00
Symposium soirée at The Liberty Hotel
Day 3 - October 10
8:00 - 12:00
MORNING SESSION
8:00
Management guidelines
9:00
Are there really just four IgG4-RD subsets?
9:30
On the contrary, IgG4-RD is not a pre-malignant condition
10:00
Break
10:15
IgG4-related sclerosing cholangitis
10:45
Do overlap conditions between IgG4-RD and other discrete diseases truly exist?
11:15
Managing the atopic features of IgG4-RD
12:00
Lunch
1:15 - 3:00
AFTERNOON SESSION
1:15
The natural history of AIP by imaging
1:45
Coronary vasculitis and peri-arteritis in IgG4-RD: How do we diagnose, treat, and manage it?
2:15
What will the treatment and management of IgG4-RD look like in 2030?
2:45
Break
03:00
Identification of the seventh symposium site in 2028
3:15
Closing remarks
Host
Dr. John Stone
IgG4ward! Executive Chairman, Rheumatologist
Massachusetts General Hospital